Dupilumab Auto-Injector (DUPILUMAB - INJECTION)

Instructions

This medicine is injected into the skin. Ask your doctor, nurse, or pharmacist where on your body this medicine can be injected and how to inject it.

The liquid should be clear or light yellow.

Check the medicine before each use. If the liquid medicine has any particles in it, appears discolored, or if the vial appears damaged, do not use it.

Do not shake the medicine before using.

Store new medicine in the refrigerator until you are ready to use it. Do not allow them to freeze.

Keep the medicine in its original container.

If the medicine becomes frozen, you will need to throw it away.

If needed, this medicine may be stored at room temperature for 14 days or less.

Protect medicine from light.

If your medicine is stored in the refrigerator, take it out of the refrigerator about 45 minutes before use to warm to room temperature.

Injecting cold drug may be uncomfortable.

Discard unused medicine after 14 days at room temperature.

Never use any medicine that has expired.

Wash your hands before and after handling this medicine.

You or a family member can be trained to give this medicine at home.

Avoid injecting the medicine within 2 inches around the navel.

Do not inject into skin that is red, swollen or itchy.

If your dose is 2 syringes or injections, inject each in 2 different locations.

Change the location of the injection each time. Choose a location at least 1 inch from the last injection.

Do not rub or massage the area where the injection was given.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Talk to your doctor before taking other medicines, including aspirins and ibuprofen containing products. Speak to your doctor about which medicines are safe to use while you are on this medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

Speak with your health care provider before receiving any vaccinations.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Ask your doctor, nurse or pharmacist how to safely discard unused medicines, needles and syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• dry eyes
• pain, redness, swelling near injection

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• blurry vision
• eye pain or redness
• pain in the joints
• shortness of breath
• blurring or changes of vision

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.