Ketorolac Metered Dose Nasal Spray (KETOROLAC SPRAY - NASAL)

Instructions

Keep the medicine in the refrigerator until you are ready to use it. Do not freeze. Remove from the refrigerator and let it warm up to room temperature before using. Keep the medicine at room temperature once opened. Do not put it back into the refrigerator.

This medicine is for use in the nose. Avoid getting the medicine into the eyes or mouth. Rinse the eyes with water if the medicine is sprayed into the eyes.

Ask your doctor, nurse or pharmacist to show you how to use this medicine correctly.

Keep the medicine in the package until you are ready to use it.

The first time you open a new spray bottle, you need to get it ready to use. Point the bottle away from you and spray into the air 5 times. You should see some medicine come out while doing this. It is now ready to use. This process is called priming the spray.

Wash your hands before and after handling this medicine.

Drink plenty of water while on this medicine.

Blow and wipe your nose with a clean tissue before using this product.

Sit up straight or stand, and tilt the head slightly forward before spraying.

Insert the tip of the spray bottle into the nostril. Spray into the nostril by pressing down evenly on both sides of the pump.

Do not spray the medicine directly on the middle wall of your nose (nasal septum).

Do not sniff, swallow, or inhale through the nose while using the spray.

If your dose is 2 sprays, spray second into other nostril.

If you forget a dose, you may skip it and continue your regular schedule.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Talk to your doctor before taking other medicines, including aspirins and ibuprofen containing products. Speak to your doctor about which medicines are safe to use while you are on this medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Discard any unused medicine 24 hours after opening.

Do not share this medicine with anyone who has not been prescribed this medicine.

Keep all appointments for medical exams and tests while on this medicine.

Do not use for more than 5 days.

Avoid storing in direct sunlight.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine is associated with an increased risk of serious heart problems, heart attack, and stroke. Please speak with your doctor about the risks and benefits of using this medicine. Contact your doctor immediately if you experience chest pain or difficulty breathing.

This medicine may cause bleeding from the stomach or bowels. Stop this medicine and call your doctor right away if you have pain in the stomach, red or dark tarry stools, or vomit that looks like coffee grounds.

Do not use the medication any more than instructed.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

Avoid smoking while on this medicine. Smoking may increase your risk for stomach bleeding.

This medicine passes into breast milk. Ask your doctor before breastfeeding.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• dizziness or drowsiness
• high blood pressure
• irritation inside the nose
• nausea
• stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• bleeding or bruising
• chest or jaw pain
• coughing up blood or vomit that looks like coffee grounds
• swelling of the legs, feet, and hands
• fever
• numbness or tingling in hands and feet
• fast or irregular heart beats
• signs of kidney damage (such as change in urine color or bubbly urine)
• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
• mood changes
• ringing in the ears
• shortness of breath
• bloody or dark, tarry stools
• symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
• swelling in the neck or throat
• blurring or changes of vision
• severe or persistent vomiting
• sudden or unexplained weight gain

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.