Desmopressin Metered Dose Nasal Spray (DESMOPRESSIN SPRAY (NOCTURIA) - NASAL)

Instructions

Do not shake the medicine before using.

Keep the medicine in the refrigerator until you are ready to use it. Do not freeze. Remove from the refrigerator and let it warm up to room temperature before using. Keep the medicine at room temperature once opened. Do not put it back into the refrigerator.

This medicine is for use in the nose. Avoid getting the medicine into the eyes or mouth. Rinse the eyes with water if the medicine is sprayed into the eyes.

Ask your doctor, nurse or pharmacist to show you how to use this medicine correctly.

The first time you open a new spray, you need to get it ready to use. Point the bottle away from you and spray into the air. Repeat until you see a fine mist. It is now ready to use. This process is called priming the spray.

Read and carefully follow package instructions for preparing, using and cleaning the pump.

Do not drink a lot of water or other beverages close to bedtime while using this medicine.

Blow and wipe your nose with a clean tissue before using this product.

Do not spray the medicine directly on the middle wall of your nose (nasal septum).

Tell your doctor if you have severe or persistent sweating, diarrhea or vomiting. These can increase your risk of a serious side effect.

If you forget a dose, you may skip it and continue your regular schedule.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Store in original bottle, tightly closed and upright.

Discard any unused medicine after 60 days.

Do not share this nasal spray with other people. Doing so may spread infections.

Keep all appointments for medical exams and tests while on this medicine.

Do not take the medicine more than once during 24 hours.

Cautions

This medicine is not approved for use in children younger than 18.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

Please check with your doctor before drinking alcohol while on this medicine.

Avoid becoming overheated during exercise or other activities. Try to stay cool in hot weather.

Call the doctor if there are any signs of confusion or unusual changes in behavior.

Contact your doctor if you develop any signs of a new infection such as fever, cough, sore throat, or chills.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• nosebleeds
• feeling of heat or flushing
• irritation inside the nose
• nausea
• sneezing

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• confusion
• dizziness or drowsiness
• severe or persistent headache
• high blood pressure
• mood changes
• muscle cramps
• restlessness
• seizures
• unusual or unexplained tiredness or weakness

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.