Rotigotine Transdermal System (ROTIGOTINE PATCH - TRANSDERMAL)

Instructions

Keep the medicine at room temperature. Avoid heat and direct light.

This patch should not be cut.

Wash your hands before and after handling this medicine.

Do not remove the patch from its package until you are ready to use it.

Remove old patch before applying new one. Change the location of the new patch.

Do not use if the pouch containing the medicine is torn or damaged.

Do not use the patch if it is broken, cut, or damaged.

Remove the plastic liner that protects the sticky side of the patch before applying to the skin.

Do not use soap, oils, or alcohol on the area of the skin before applying the patch. Use only water and gently pat dry. Do not rub the skin.

Apply the patch to a clean, dry, hairless area. Avoid skin that is red, scraped, or damaged.

Press the patch firmly for a few seconds to make sure it stays in place.

If the edges of the patch begin to peel up you may tape the edges down with first aid tape. Do not cover the entire patch.

After removing the patch, fold it together and discard it out of reach of children and pets, NOT in the toilet.

Avoid getting the medicine in the eyes, nose, or mouth. Wash your hands after touching patch.

To avoid skin irritation, wait at least two weeks before using the patch on same location again.

Do not apply heat on the area with the patch. Avoid heating blankets, suntan beds, or hot tubs.

You can bathe, swim, or shower while wearing the patch. Clothing may be worn over the patch.

Remove patch if it causes pain or burning.

Use baby oil or mineral oil to remove any stickiness that remains after washing the skin. Do not use solvents like alcohol or acetone.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Cautions

If you stop this medicine suddenly after using it regularly for a long time, you may have withdrawal. Your doctor may slowly reduce your dose before stopping it. Tell your doctor right away if you notice any symptoms of withdrawal. Withdrawal symptoms can include anxiety, depression, confusion, fever, or muscle stiffness.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

This medicine may cause dizziness or fainting. Do not stand or sit up quickly.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• agitated feeling or trouble sleeping
• decreased appetite
• high or low blood pressure
• dizziness or drowsiness
• headaches
• nausea and vomiting

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• confusion
• depression or feeling sad
• swelling of the legs, feet, and hands
• fainting
• hallucinations (unusual thoughts, seeing or hearing things that are not real)
• fast or irregular heart beats
• unusual strong urges - such as increased need to shop, gamble, or have sex
• uncontrollable movement of face, tongue, arms or legs
• tight or rigid muscles
• falling asleep suddenly during usual daily activities
• sweating
• weight gain

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.