Paxlovid 5-Day Oral Tablet 150 mg/100 mg (nirmatrelvir/ritonavir) (NIRMATRELVIR/RITONAVIR - ORAL)

Instructions

Swallow the medicine without crushing or chewing it.

This medicine may be taken with or without food.

This medicine will work best if you take it at about the same time every day.

Space doses evenly to keep a steady amount of medicine in the body.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

If you forget to take a dose on time, take it if you remember within 8 hours of the scheduled dose. If you don’t remember until after more than 8 hours, skip the missed dose and return to your regular schedule with the next dose. Do not take 2 doses of this medicine at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

This medicine may decrease the effectiveness of some birth controls which use hormones (such as birth control pills and patches). Use an extra form of birth control, such as condoms, while on this medicine.

Keep all appointments for medical exams and tests while on this medicine.

Continue to wear a mask, practice social distancing, and follow other safety guidelines to protect yourself and those around you until otherwise directed.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Do not take St. John's wort while on this medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

• diarrhea
• changes in taste or unpleasant taste

Call your doctor or get medical help right away if you notice any of these more serious side effects:

• signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.